Most Viewed Articles

Mini Review Drug nanotargeting for treatment of neurodegeneration and aging Joseph S. D'Arrigo Published: Tuesday, June 29, 2021 Viewed: 74731

Therapeutic Brief The potential of GHK as an anti-aging peptide Warren Ladiges, Yan Dou, Amanda Lee, Lida Zhu, John Morton Published: Friday, March 27, 2020 Viewed: 10625

Research Article Sleep-deprived cognitive impairment in aging mice is alleviated by rapamycin Warren Ladiges, Kishore Mukherjee, Amanda Lee, Lida Zhu, Martin Darvas Published: Monday, December 30, 2019 Viewed: 7565

Conference Abstract Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging Warren Ladiges, Yuji Ikeno, Liang Wang Published: Friday, March 27, 2020 Viewed: 7537

Review The rationale for testing drug combinations in aging intervention studies Kavita C Sharma, Juan Wang, Zhou Jiang, Jenna Klug, Martin Darvas, Denise M Imai, Timothy Snider, Laura Niedernhofer, Warren C Ladiges Published: Monday, December 30, 2019 Viewed: 7163

Case Report Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations Junko Oshima, Renuka Kandhaya-Pillai, Fuki M Hisama, Stephanie A Bucks, Soe Yarzar, Haroula Korovou, George M Martin Published: Monday, June 29, 2020 Viewed: 7160

Review Development of a Geropathology Grading Platform for nonhuman primates Warren Ladiges, Katie J Olstad, Denise M Imai, Rebekah I Keesler, Rachel Reader, John H Morrison, Jeffery A Roberts, John P Capitanio, Elizabeth S Didier, Marcelo J Kuroda, Heather Simmons, Shabnam Salimi, Julie A Mattison, Yuji Ikeno Published: Friday, March 27, 2020 Viewed: 6900

Research Article Highly expressed ribosomal protein L34 predicts poor prognosis in acute myeloid leukemia and could be a potential therapy target Liang Wang, Jing Yang, Henan Wang, Weida Wang, Xiaojie Liang Published: Friday, March 27, 2020 Viewed: 6819

Case Report Irreversible effects of anticholinergic withdrawal in the elderly: a case report Charisse Chehovich, Claudia Lee, Tammie Lee Demler Published: Tuesday, June 29, 2021 Viewed: 6727

Research Article Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice Madeline G. Roman, Lisa C. Flores, Geneva M. Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Thomas L. Saunders, Yuji Ikeno Published: Friday, March 27, 2020 Viewed: 6632

Technology Feature QuPath. A new digital imaging tool for geropathology Warren Ladiges, Amanda Lee, Zhou Jiang, Lida Zhu Published: Monday, June 29, 2020 Viewed: 6383

Research Article LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression Jianda Dong, Pihong Li, Xiaoyu Pan, Zhouci Zheng, Yihan Sun, Yifan Han Published: Monday, June 29, 2020 Viewed: 6374

Research Article Interfering with miR-24 alleviates rotenone-induced dopaminergic neuron injury via enhancing autophagy by upregulating DJ-1 Fengrui Li, Biao Ge, Hairong Wu, Dan Shao, Shulin Li Published: Monday, December 30, 2019 Viewed: 6257

Model Profile The CB6F1 mouse is a model for studying cognition and brain morphometry with increasing age Warren Ladiges, Davika Gandhay, Christina Pettan Brewer Published: Wednesday, March 29, 2023 Viewed: 6164

Case Report Drug-Induced Hemolytic Crisis During Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma: A Rare Hematologic Adverse Reaction Xin Wen, Liang Wang, Yingzhi He, Shan Wang Published: Monday, December 30, 2019 Viewed: 6160

Research Article MicroRNA-152 suppresses cell proliferation and tumor growth of bladder cancer by targeting KLF5 and MKK7 Liangliang Wang, Yu Hui, Yuhua Huang, Xiang Ding Published: Monday, December 30, 2019 Viewed: 5989

Research Article Down-regulation of miR-181a promotes microglial M1 polarization through increasing expression of NDRG2 Bo Zhou, Yali Niu, Chunxiao Wan, Rui wu, Heying Sun, Danqing Lu Published: Friday, March 27, 2020 Viewed: 5967

Editorial Time for an Alzheimer’s disease cocktail Warren Carl Ladiges Published: Friday, March 27, 2020 Viewed: 5808

Review Aging pet cats develop neuropathology similar to human Alzheimer’s disease Warren Ladiges, Jenna Klug, Jessica M. Snyder, Martin Darvas, Denise M. Imai, Molly Church, Caitlin Latimer, C . Dirk Keene Published: Tuesday, September 29, 2020 Viewed: 5797

Research Article Mitochondrial-targeted methionine sulfoxide reductase overexpression increases the production of oxidative stress in mitochondria from skeletal muscle Adam B. Salmon, Arunabh Bhattacharya, Daniel Pulliam, Yuhong Liu Published: Friday, March 27, 2020 Viewed: 5668

Research Article Pioglitazone up-regulates MALAT1 and promotes the proliferation of endothelial progenitor cells through increasing c-Myc expression in type 2 diabetes mellitus Xiaoxu Yang, Chen Hu, Yan Sun Published: Friday, March 27, 2020 Viewed: 5490

Review Thioredoxin and aging: What have we learned from the survival studies? Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Gene Borden Hubbard, Yidong Bai, Thomas L. Saunders, Yuji Ikeno Published: Tuesday, September 29, 2020 Viewed: 5298

Research Article IL-17 regulates the expression of major histocompatibility complex II and VEGF in DLBCL mice on tumor growth Xin Xu, Ting Wei, Weijie Zhong, Zhigang Zhu, Feng Liu, Qingshan Li Published: Monday, June 29, 2020 Viewed: 5180

Editorial Progress in drug treatment of elderly chronic heart failure Feng Liu, Siting Zhang Published: Thursday, December 31, 2020 Viewed: 5177

Research Article Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment Warren Ladiges, Amanda Lee, Haoyi Lei, Lida Zhu, Zhou Jiang Published: Thursday, December 31, 2020 Viewed: 5136

Technology Feature An immune stress test for resilience to aging: Pneumococcal vaccine response Warren Ladiges, Ryan Oveson, Zhou Jiang, Michali Izhak, Kavita Sharma Published: Tuesday, September 29, 2020 Viewed: 5117

Review Guidelines for the Prevention of Coronavirus Pneumonia in Elderly People Wei Ma, Jun Zhao, Gang Xu, Congrui Feng, Yuluo Chen, Feng Liu Published: Monday, June 29, 2020 Viewed: 5094

Research Article Sex-dependent lifespan extension of ApcMin/+ FAP mice by chronic mTOR inhibition Manish Parihar, Sherry G Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Dave Sharp Published: Thursday, December 31, 2020 Viewed: 5076

Model Profile A mouse model of sleep deprived neuropathology to study resilience to Alzheimer’s disease Warren Ladiges, Yan Dou, Jinzi Wu, Lida Zhu, Martin Darvas Published: Monday, June 29, 2020 Viewed: 5011

Review The cellular senescence unification model and telomerase therapy: To treat all age-related diseases Steve Liebich Published: Tuesday, September 29, 2020 Viewed: 4997

Review Gastrointestinal Disasters of Cetuximab in the Treatment of Metastatic Colorectal Cancer: Mechanism and its Effect on Prognosis Junfeng Sun, Yue Wu, Haowei Jia, Xinqi Bao, Tianyu Zhu, Ruixin Li, Hongchao Zhao Published: Monday, June 29, 2020 Viewed: 4976

Editorial Oxidative stress in aging: stayin’ alive? Lisa C. Flores, Yuji Ikeno Published: Monday, June 29, 2020 Viewed: 4962

Research Article Finding prodromal frailty in a community-dwelling healthy older cohort by survey of BDNF or hand grip strength classified by BMI Mitsugu Hachisu, Masahiro Hashizume, Hisashi Kawai, Motonaga Kojima, Yoshinori Fujiwara, Shuichi Obuchi, Mari Kogo, Masayuki Ohbayashi, Noriko Koyama, Miki Takenaka, Kazushige Ihara Published: Tuesday, September 29, 2020 Viewed: 4936

Model Profile A model for studying cutaneous wound healing and resilience to aging: Ear punch biopsy in old mice Warren Ladiges, Zhou Jiang, Jessie Chen, Juan Wang, Ruby Mangalindan, Lida Zhu Published: Tuesday, September 29, 2020 Viewed: 4924

Research Article Anti-tumor effect of pcDNA3.1(-)/rMETase-shUCA1 hyaluronic acid-modified G5 polyamidoamine nanoparticles on gastric cancer Chunying Xie, Zhenxing Huang, Zhaohui Huang, Yanyan Guo, Xue Zhang Published: Monday, June 29, 2020 Viewed: 4813

Therapeutic Brief Short-term oral rapamycin prevents age-related learning impairment in mice Warren Ladiges, Haoyi Lei, Juan Wang, Zhou Jiang Published: Tuesday, September 29, 2020 Viewed: 4812

Geropathology Notes Eosinophilic crystalline pneumonia, an age-related lesion in mice Jenna J Klug, Jessica M Snyder Published: Thursday, December 31, 2020 Viewed: 4768

Commentary A geropathology approach for identifying therapeutic targets to prevent pathological complications of COVID-19 Warren Ladiges, Yuji Ikeno, Liang Wang, Feng Liu Published: Monday, June 29, 2020 Viewed: 4711

Therapeutic Brief Physical performance is enhanced in old mice fed a short term diet medicated with rapamycin, acarbose, and phenylbutyrate Warren Ladiges, Megan Ellis, Zhou Jiang Published: Monday, March 29, 2021 Viewed: 4704

Therapeutic Brief The potential of XPO1 inhibitors as a game changer in relapsed/refractory hematologic malignancies Henan Wang, Liang Wang, Jing Yang Published: Monday, June 29, 2020 Viewed: 4666

Review Myocardial Cell Aging in the Elderly Feng Liu, Wenxi Li Published: Tuesday, September 29, 2020 Viewed: 4649

Model Profile Neutrophil response to cyclophosphamide predicts resilience to age-related learning impairment Lida Zhu, Warren Ladiges, Katie Nickel, Marianne Bjorner Published: Thursday, December 31, 2020 Viewed: 4457

Research Article miR-181c inhibits prostatic epithelial cell proliferation caused by chronic non-bacterial prostatitis through down-regulating COX-2 Xiang Ding, Xu Xu, Yuhua Huang, Jianquan Hou, Jinxing Lv Published: Thursday, December 31, 2020 Viewed: 4431

Case Report Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study Eleonora Duregon, Rafael de Cabo, Camila Vieira Ligo Teixeira, Dushani L. Palliyaguru, Annamaria L. Rudderow, Victoria Hoffmann, Michel Bernier, Nathan L. Price, Simonetta Camandola Published: Thursday, December 31, 2020 Viewed: 4398

Commentary Resilience to aging is a heterogeneous characteristic defined by physical stressors Haoyi Lei, Derek M. Huffman, Adam B. Salmon, Nathan K. LeBrasseur, Christy Carter, Arlan Richardson, Steve Austad, Warren Ladiges Published: Wednesday, March 30, 2022 Viewed: 4375

Research Article Thioredoxin down-regulation in the cytosol in thioredoxin 2 transgenic mice did not have beneficial effects to extend lifespan in male C57BL/6 mice Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Yidong Bai, Gene B. Hubbard, Yuji Ikeno Published: Thursday, December 31, 2020 Viewed: 4363

Therapeutic Brief Gam-COVID-Vac (Sputnik V): a heterologous adenoviral vector-based COVID-19 vaccine Shyh Poh Teo, Sanny Zi Lung Choo Published: Tuesday, June 29, 2021 Viewed: 4354

Review Recent advances in the genetic association between osteoporotic fracture and sarcopenia Qiaocong Chen, Huiling Lou, Cheng Peng Published: Monday, March 29, 2021 Viewed: 4295

Review Application and research progress of BCL2 inhibitors in elderly patients with hematologic malignancies Liang Wang, Yufan Wang Published: Thursday, December 31, 2020 Viewed: 4234

Geropathology Notes Hepatic steatosis, a lesion reported in captive aged common marmosets Sebastian Eduardo Carrasco, Olga Lucia Franco-Mahecha Published: Monday, March 29, 2021 Viewed: 4227

Therapeutic Brief Denosumab for the treatment of osteoporosis Shyh Poh Teo Published: Tuesday, September 29, 2020 Viewed: 4180

Case Report Coronary artery stenosis regression by long-term standard dose statin therapy in middle-aged and elderly patients: Report and analysis of 31 cases Feng Liu, Zhilei Ren, Chongzhe Yang, Kaihua Huang Published: Tuesday, September 29, 2020 Viewed: 4145

Letter to Editor Optimal induction treatment regimens for extranodal NK/T-cell lymphoma: lessons learned, challenges, and proposals Liang Wang, Jing Yang, Ruiying Fu, Xindi Liu, Liqiang Wei Published: Thursday, December 31, 2020 Viewed: 4083

Research Article PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging Warren Ladiges, Shabnam Salimi, Christina Pettan-Brewer Published: Friday, December 31, 2021 Viewed: 4078

Editorial Immunotherapy: the blockbuster in cancer treatment Liang Wang Published: Tuesday, September 29, 2020 Viewed: 4075

Case Report Castleman disease with rapidly progressive pemphigus: case report Liang Wang, Ruiying Fu, Yingzhi He Published: Thursday, December 31, 2020 Viewed: 4057

Review Safety and efficacy of the Novavax vaccine—a narrative review Shyh Poh Teo, Sanny Zi Lung Choo Published: Friday, December 31, 2021 Viewed: 4053

Editorial Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging Michal M. Masternak, Hariom Yadav Published: Wednesday, March 30, 2022 Viewed: 4040

Research Article Di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone effectively induces human colorectal carcinoma cell apoptosis via mTOR pathway Qianqian Fu, Shengli Wang, Chuyun Zhu, Zhenlong Zhou, Xiaojuan Yu, Yong Zhang Published: Thursday, September 30, 2021 Viewed: 4020

Letter to Editor Arthritis as an adverse event of special interest post COVID-19 vaccine implementation Shyh Poh Teo Published: Monday, March 29, 2021 Viewed: 4011

Research Article KDClassifier: A urinary proteomic spectra analysis tool based on machine learning for the classification of kidney diseases Wanjun Zhao, Yong Zhang, Xinming Li, Yonghong Mao, Changwei Wu, Lijun Zhao, Fang Liu, Jingqiang Zhu, Jingqiu Cheng, Hao Yang, Guisen Li Published: Thursday, September 30, 2021 Viewed: 4008

Research Article Association of anemia with rehabilitation outcome for subacute geriatric rehabilitation patients in a secondary hospital in malaysia Mann Leon Chin, Christopher WS Chan, Huey Ee Chong, Wee Kooi Cheah Published: Friday, December 31, 2021 Viewed: 3985

Editorial Harnessing the heterogeneity of aging Warren Ladiges Published: Monday, March 29, 2021 Viewed: 3979

Commentary Geropathology. An inside view of biological aging Warren Ladiges Published: Wednesday, March 30, 2022 Viewed: 3903

Reviewer Acknowledgement 2020 Reviewer Acknowledgment Editorial Office of Aging Pathobiology and Therapeutics Published: Thursday, December 31, 2020 Viewed: 3763

Research Article Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older subjects: meta-analysis Guangqin Zou, Quan Wang, Hua Wan, Xiang Lu, Wei Gao Published: Wednesday, March 30, 2022 Viewed: 3742

Commentary The unrecognized potential of pet cats for studying aging and age-related diseases Warren Ladiges Published: Friday, December 31, 2021 Viewed: 3737

Editorial Chimeric antigen receptor T cell therapy in cancer: Advances and challenges Yuanzheng Liang, Liang Wang Published: Thursday, September 30, 2021 Viewed: 3733

Review Advances in targeting programmed cell death 1/programmed cell death-ligand 1 therapy for hematological malignancies Liang Wang, Yuanzheng Liang, Wanying Zhao Published: Friday, December 31, 2021 Viewed: 3691

Therapeutic Brief The antidiabetic drug acarbose suppresses age-related lesions in C57BL/6 mice in an organ dependent manner Zhou Jiang, Sneh Gupta, Warren Ladiges Published: Tuesday, June 29, 2021 Viewed: 3657

Review Progress on the study of fibroblast growth factors as novel therapeutics in post-stroke cognitive impairment Hong Fan, Mengqi Li Published: Thursday, September 30, 2021 Viewed: 3650

Case Report Cardiac arrest in an older male patient treated with flecainide for atrial fibrillation Tiziana Ciarambino, Rosario Bottone, Gennaro Sansone, Mauro Giordano Published: Tuesday, June 29, 2021 Viewed: 3602

Case Report A fornix infarction causing post-operative anterograde amnesia Shyh Poh Teo Published: Tuesday, June 29, 2021 Viewed: 3576

Commentary Precision aging. Human lifespan has intrinsic limits but measurable outcomes Warren Ladiges Published: Tuesday, June 29, 2021 Viewed: 3522

Research Article Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice Kaitlin Nickel, Lida Zhu, Ruby Mangalindan, Jessica M. Snyder, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, Jenna Klug, Zhou Jiang, David J. Marcinek, Peter Rabinovitch, Warren Ladiges, Matthew Tucker Published: Friday, September 30, 2022 Viewed: 3519

Editorial Thioredoxin – a magic bullet or a double-edged sword for mammalian aging? Yuji Ikeno Published: Tuesday, June 29, 2021 Viewed: 3502

Case Report Older female relatives of Covid-19 patients have an un-satisfactory perception of emergency room performance by clinical staff Tiziana Ciarambino, Luigia Palmiero, Rosario Bottone, Federico Schettini, Luigi Elio Adinolfi, Mauro Giordano Published: Tuesday, June 29, 2021 Viewed: 3447

Commentary Mouse modeling for anxiety disorders in older adults Martin Darvas, Warren Ladiges, Nadia Postupna Published: Thursday, September 30, 2021 Viewed: 3409

Research Article Clinical diagnosis and treatment of primary small intestinal lymphoma Guitian Huang Published: Thursday, September 30, 2021 Viewed: 3343

Letter to Editor Preventive effect of rehabilitation training therapy on muscle quality in patients with stroke: A retrospective study Xiang Lu, Dandan Feng, Wei Gao, Can Zhao, Dan Chen, Xiaojing He Published: Friday, December 31, 2021 Viewed: 3320

Conference Abstract The aging immune system. Abstracts presented at the Masoro-Barshop conference on aging, October 13-15, 2021 Warren Ladiges Published: Friday, December 31, 2021 Viewed: 3294

Case Report Nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis: a Case report and literature review Xuelin Liu, Liqiang Wei, Jing Yang, Jin Ye, Liang Wang Published: Wednesday, March 30, 2022 Viewed: 3279

Review Mechanisms of autophagy regulation by adiponectin Xin Xu, Chan Rong Published: Friday, December 31, 2021 Viewed: 3185

Commentary Pharmaceutical interventions to slow human aging. Are we ready for cocktails? Warren Ladiges, Manuela Rosenfeld Published: Thursday, June 30, 2022 Viewed: 2781

Review The critical role of macrophages in ovarian cancer treatment Yiran Wang, Mingyi Wang Published: Friday, September 30, 2022 Viewed: 2739

Review Vitiligo as a potential degenerative disease: from oxidative stress to cellular senescence Yaojun Wang, Jiaoni Chi, Tao Wang, Yue Zhang, Zhimin Li, Jie Chen, Haixia Liu, Qiang Li Published: Thursday, June 30, 2022 Viewed: 2728

Review Evidence for an alternative insulin transporter at the blood-brain barrier Elizabeth M Rhea, William A Banks, Cassidy Noonan Published: Tuesday, May 23, 2023 Viewed: 2503

Reviewer Acknowledgement 2021 Reviewer Acknowledgment Editorial Office of Aging Pathobiology and Therapeutics Published: Friday, December 31, 2021 Viewed: 2445

Model Profile A mouse model of naturally occurring age-related cognitive impairment Sara Daneshjoo, Jualiana Moreno, Manuela Rosenfeld, Joo Young Park, Martin Darvas, Warren Ladiges Published: Friday, September 30, 2022 Viewed: 2428

Editorial Get back–calorie restriction: Dr. Masoro’s legacy Yuji Ikeno, Lisa C. Flores Published: Thursday, June 30, 2022 Viewed: 2424

Review Age effect on mesenchymal stem cell properties: A concise review Tsz Kin Ng, Chong-Bo Chen, Xin Bin, Yuqiang Huang, Herman S. Cheung Published: Tuesday, May 23, 2023 Viewed: 2362

Mini Review Sotrovimab for treatment of COVID-19 infections Shyh Poh Teo Published: Thursday, June 30, 2022 Viewed: 2350

Therapeutic Brief Molecular hydrogen may activate the transcription factor Nrf2 to alleviate oxidative stress through the hydrogen-targeted porphyrin Shigeo Ohta Published: Tuesday, May 23, 2023 Viewed: 2331

Review Research progress in the PD-1/PD-L1 pathway and IL-17A in lymphomas Li Yang, Xin Xu Published: Thursday, June 30, 2022 Viewed: 2206

Editorial Targeting metabolism through exercise and nutrition to rejuvenate an aging immune system Brandt D. Pence Published: Friday, September 30, 2022 Viewed: 2204

Therapeutic Brief Difference in the effectiveness of subthalamic nucleus and globus pallidus deep brain stimulation in Parkinson’s disease Hushyar Azari Published: Thursday, June 30, 2022 Viewed: 2199

Commentary Sex Matters in Aging. The Canagliflozin Story Warren Ladiges, Jackson Wezeman Published: Friday, September 30, 2022 Viewed: 2197

Review Sarcopenia and falls in older adults Chieh Chen, Daming Liao Published: Friday, September 30, 2022 Viewed: 2177

Research Article A reappraisal of the measured concentration of voriconazole based on plasma albumin concentration during its therapeutic drug monitoring Fangmin Xu, Yexuan Wang, Xiaoshan Zhang, Junhui Yu, Liwen Zhang, Xuben Yu, Haina Zhang Published: Thursday, June 30, 2022 Viewed: 2150

Commentary Targeting IGF1R signaling for brain aging and Alzheimer’s disease Warren Ladiges, Joo Young Park, Martin Darvas Published: Thursday, December 29, 2022 Viewed: 2145

Interview On the growth of young neurologists—an interview with Prof. Louis R. Caplan Qi Qin Published: Friday, September 30, 2022 Viewed: 2136

Mini Review Human microbiota alterations — emerging predictors of renal diseases and kidney-specific aging Chao Zhao, Miaomiao Pan, Ming Zhang, Xingyu Rong Published: Wednesday, March 29, 2023 Viewed: 2131

Review Senescence of mesenchymal stem cells: implications in extracellular vesicles, miRNAs and their functional and therapeutic potentials Guangqian Zhou, Liangge He, Mingzhu Li, Zhen Liu, Arshad Ahmed Padhiar Published: Tuesday, October 17, 2023 Viewed: 2051

Review Influence of metformin on age-related macular degeneration Albert J Augustin, Jenny Atorf Published: Tuesday, May 23, 2023 Viewed: 2046

Interview On the frontier of immunogerontology—an interview with Prof. Graham Pawelec Xiaodong Li Published: Friday, September 30, 2022 Viewed: 2004

Commentary The Eph receptor A4-mediated demyelination in depression Quanguang Zhang, Luodan Yang Published: Thursday, December 29, 2022 Viewed: 1996

Interview On the original aspiration of researching neurodegenerative diseases—an interview with Prof. Jeffrey Kordower Min Zhu Published: Thursday, December 29, 2022 Viewed: 1978

Interview On the frontier of chronic obstructive pulmonary disease—an interview with Prof. Peter J Barnes Wei Ma Published: Thursday, December 29, 2022 Viewed: 1945

Therapeutic Brief GHK peptide prevents sleep deprived learning impairment in aging mice Warren Ladiges, Manuela Rosenfeld, Katie Nickel Published: Wednesday, March 29, 2023 Viewed: 1906

Commentary In vitro geroscience. Screening anti-aging drug combinations for neurodegenerative diseases Warren Ladiges, Soroosh Fatemi, Joo Young Park Published: Wednesday, June 28, 2023 Viewed: 1859

Mini Review Role of fibro-adipogenic progenitors in skeletal muscle aging Renwen Wan, Hanli Zhang, Shan Liu, Chunmeng Jiao, Hui Chen, Zhiwen Luo, Xiliang Shang Published: Wednesday, June 28, 2023 Viewed: 1852

Editorial Is aging “normal”? Warren Ladiges, Chloe Johnson Published: Thursday, December 29, 2022 Viewed: 1753

Research Article Additional polgD257A mutation (mutator) does not influence dopaminergic neurodegeneration in aged parkin-deficient mice Xin-Ran Zhu, David Mrohs, Max Rybarski, Michael Andriske, Pauline Bohne, Melanie D. Mark, Hermann Lübbert Published: Tuesday, May 23, 2023 Viewed: 1657

Editorial Biological age from a pathological perspective Warren Ladiges Published: Wednesday, March 29, 2023 Viewed: 1651

Research Article Targeted regulation of senescence-associated secretory phenotype with an aptamer-conjugated activatable senomorphic Yanlan Liu, Yuqi Xie, Jili Li, Pingyu Wu, Linlin Wang, Donghui Hong, Jian Wang Published: Wednesday, June 28, 2023 Viewed: 1548

Review Nrf2 participates in progression of osteoarthritis through modulating redox balance Yueqi Chen, Zihan Deng, Chuan Yang Published: Thursday, September 28, 2023 Viewed: 1412

Editorial Ethylnitrosourea-induced gliomas: a song in the attic? Yuji Ikeno Published: Wednesday, June 28, 2023 Viewed: 1371

Case Report The case of a geriatric female experiencing frequent falls and epileptic seizures during long-term low-dose clozapine and extended-release bupropion treatment Charisse Dzierba, Claudia Lee, Tammie Lee Demler Published: Wednesday, June 28, 2023 Viewed: 1285

Reviewer Acknowledgement 2022 Reviewer Acknowledgment Editorial Office of Aging Pathobiology and Therapeutics Published: Thursday, December 29, 2022 Viewed: 1269

Review Cardiovascular aging in patients with chronic kidney disease: pathogenesis and potential therapeutics Safa Alkhayyat, Mohamed Abdalbary, Zahraa Alhoori Published: Thursday, September 28, 2023 Viewed: 1189

Editorial Physical resilience is a predictor of healthy aging Warren Ladiges Published: Thursday, September 28, 2023 Viewed: 1173

Research Article Older-aged C57BL/6 mice fed a diet high in saturated fat and sucrose for ten months show decreased resilience to aging Chloe N Johnson, Lida Zhu, Ruby Mangalindan, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, David J. Marcinek, Peter Rabinovitch, Warren Ladiges Published: Thursday, September 28, 2023 Viewed: 1083

Mini Review Biobased nanoemulsions for targeted drug delivery to treat dementia and aging Joseph S. D'Arrigo Published: Thursday, September 28, 2023 Viewed: 1074

Review The role of immune aging in giant cell arteritis Patricia Harkins, Sharon Cowley, Robert Harrington, David Kane, Richard Conway Published: Thursday, September 28, 2023 Viewed: 1043

Review A review of variable risk factors affecting the development of mild cognitive impairment in older adults Chenghui Zhang, Hong Fan, Mengqi Li Published: Tuesday, December 26, 2023 Viewed: 1035

Mini Review Modeling resilience to sleep disruption to study resistance to Alzheimer’s disease Warren Ladiges, Jordan Mazzola, Joo Young Park Published: Tuesday, December 26, 2023 Viewed: 1026

Research Article Carvacrol induces osteogenic differentiation of BMSCs and alleviates osteolysis in aged mice by upregulating lncRNA NEAT1 to promote SIRT1 expression Zefeng Xu, Zeyu Wang, Wenming Ma, Zhihui Huang Published: Tuesday, December 26, 2023 Viewed: 1022

Research Article Statins adherence and associated muscle symptoms in elderly coronary heart disease patients Marat V Ezhov, Marina G. Bubnovaa, David M. Aronov Published: Tuesday, December 26, 2023 Viewed: 985

Interview On the treatment of Parkinson’s disease—an interview with Prof. Nir Giladi Siyan Chen Published: Tuesday, December 26, 2023 Viewed: 985

Interview On epigenetic clocks and cancer risk—an interview with Prof. Andrew E. Teschendorf Shikha Sharma Published: Tuesday, December 26, 2023 Viewed: 984

Research Article Voluntary wheel running is a non-invasive test to measure physical performance in aging mice Christina Pettan-Brewer, Addison Keely, Warren Ladiges Published: Tuesday, December 26, 2023 Viewed: 930

Editorial Importance of coordination of regional stroke centers for acute ischemic stroke Xin Xu, Yingjun Ouyang, Chan Rong Published: Tuesday, December 26, 2023 Viewed: 899

Commentary Resilience to aging drives personalized intervention strategies for Alzheimer’s disease Warren Ladiges, Jackson Wezeman, Addison Keely Published: Tuesday, December 26, 2023 Viewed: 886

Research Article Serum elementomic analysis indicates a panel of elements related with age Hui-Xian Sun, Kai-Yue Jia, Yan-Ru Li, Can Zhao, Xiang Lu, Wei Gao Published: Friday, February 23, 2024 Viewed: 783

Mini Review Research advances in stem cell transplantation combined with fibrin scaffold for treating spinal cord injury in an aging society Yongxiong He, Tianqi Jiang, Zhijun Chen, Yitong Luo, Xinyue Tian, Hua Yang Published: Thursday, March 7, 2024 Viewed: 770

Reviewer Acknowledgement 2023 Reviewer Acknowledgment Editor Office of Aging Pathobiology and Therapeutics Published: Tuesday, December 26, 2023 Viewed: 757

Research Article Exploring the complex interplay between anxiety, aging, and behavior in CB6F1 and C57BL/6 mice: implications for cognitive function Gerald Yu Liao, Kunyuan Li, Addison Keely, Shuliang Yu, Christina Pettan-Brewer, Warren Ladiges Published: Monday, March 25, 2024 Viewed: 753

Interview On the growth of young geriatricians——an interview with Prof. Louis R. Caplan Chan Rong Published: Friday, December 1, 2023 Viewed: 731

Review Exploring the interplay of leptin and aging: insights into the role of gut microbiota Harish Rangareddy, Rajhi Hayfa, Venkateshappa Chikkanarayanappa, Ashakiran Srinivasaiah, Reshma Devarajachar Published: Friday, April 12, 2024 Viewed: 726

Research Article Effects of mitochondrial fusion and fission regulation on mouse hippocampal primary cultures: relevance to Alzheimer's disease Alina Vadimovna Chaplygina, Daria Yurievna Zhdanova Published: Friday, April 12, 2024 Viewed: 722

Letter to Editor Negative health effects of low testosterone concentrations in older adults Chieh Chen, Da-Ming Liao Published: Thursday, February 29, 2024 Viewed: 679

Commentary The house cricket is an unrecognized but potentially powerful model for aging intervention studies Warren Ladiges, Gerald Yu Liao, Manuela Rosenfeld, Jackson Wezeman Published: Tuesday, March 19, 2024 Viewed: 662

Interview Improving human reproductive health and fertility——an interview with Prof. Marco G. Alves Zijian Tian Published: Thursday, May 30, 2024 Viewed: 385

Research Article Impact of oral vitamin D3 supplementation on proximal femur fracture incidence in the elderly population Hao Liu, Qingjun Qiu, Xuwen Luo, Bin Yuan Published: Thursday, June 20, 2024 Viewed: 336

Interview Focus on cytomegalovirus and cardiovascular diseases——an interview with Prof. Patricia Price Ying Li, Jianwen Chen, Yujing Fang Published: Tuesday, June 11, 2024 Viewed: 336

Review Fasting helps nutrient sensing systems in clocking the metabolism Neelu Jain Gupta Published: Tuesday, June 25, 2024 Viewed: 329

Commentary Machine learning paves the way forward for geropathology assessment Gerald Yu Liao, Jenna Klug, Warren Ladiges Published: Tuesday, June 4, 2024 Viewed: 318

Editorial Stricter definitions of myeloid senescence are needed Brandt D. Pence Published: Tuesday, June 18, 2024 Viewed: 310

Review Role of microRNAs in skin aging and its potential therapeutic interventions Deusdedit Tusubira, Ashikha Shirin Usman PP, Durairaj Sekar Published: Tuesday, June 25, 2024 Viewed: 286

Letter to Editor Periodontal disease, cardiovascular diseases and aging-the multidirectional link Madhurya N Kedlaya, Reshma Suresh, Maya Rajan Peter, Lakshmi Puzhankara Published: Tuesday, June 25, 2024 Viewed: 261

Aging Pathobiology and Therapeutics

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Aging Pathobiology and Therapeutics

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THE ANT JOURNALS

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