Most Viewed Articles
Therapeutic Brief The potential of GHK as an anti-aging peptide Warren Ladiges, Yan Dou, Amanda Lee, Lida Zhu, John Morton Published: Friday, March 27, 2020 Viewed: 4112
Research Article Sleep-deprived cognitive impairment in aging mice is alleviated by rapamycin Warren Ladiges, Kishore Mukherjee, Amanda Lee, Lida Zhu, Martin Darvas Published: Monday, December 30, 2019 Viewed: 3909
Conference Abstract Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging Warren Ladiges, Yuji Ikeno, Liang Wang Published: Friday, March 27, 2020 Viewed: 3889
Review Development of a Geropathology Grading Platform for nonhuman primates Warren Ladiges, Katie Olstad, Denise Imai, Rebekah Keesler, Rachel Reader, John Morrison, Jeffery Roberts, John Capitanio, Elizabeth Didier, Marcelo Kuroda, Heather Simmons, Shabnam Salimi, Julie Mattison, Yuji Ikeno Published: Friday, March 27, 2020 Viewed: 3672
Review The rationale for testing drug combinations in aging intervention studies Kavita Sharma, Juan Wang, Zhou Jiang, Jenna Klug, Martin Darvas, Denise Imai, Timothy Snider, Laura Niedernhofer, Warren Ladiges Published: Monday, December 30, 2019 Viewed: 3452
Research Article Highly expressed ribosomal protein L34 predicts poor prognosis in acute myeloid leukemia and could be a potential therapy target Liang Wang, Jing Yang, Henan Wang, Weida Wang, Xiaojie Liang Published: Friday, March 27, 2020 Viewed: 3359
Research Article Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice Madeline Roman, Lisa Flores, Geneva Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Thomas Saunders, Yuji Ikeno Published: Friday, March 27, 2020 Viewed: 3274
Case Report Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations Junko Oshima, Renuka Kandhaya-Pillai, Fuki Hisama, Stephanie Bucks, Soe Yarzar, Haroula Korovou, George Martin Published: Monday, June 29, 2020 Viewed: 2986
Research Article Interfering with miR-24 alleviates rotenone-induced dopaminergic neuron injury via enhancing autophagy by upregulating DJ-1 Fengrui Li, Biao Ge, Hairong Wu, Dan Shao, Shulin Li Published: Monday, December 30, 2019 Viewed: 2956
Case Report Drug-Induced Hemolytic Crisis During Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma: A Rare Hematologic Adverse Reaction Xin Wen, Liang Wang, Yingzhi He, Shan Wang Published: Monday, December 30, 2019 Viewed: 2925
Research Article MicroRNA-152 suppresses cell proliferation and tumor growth of bladder cancer by targeting KLF5 and MKK7 Liangliang Wang, Yu Hui, Yuhua Huang, Xiang Ding Published: Monday, December 30, 2019 Viewed: 2813
Research Article Down-regulation of miR-181a promotes microglial M1 polarization through increasing expression of NDRG2 Bo Zhou, Yali Niu, Chunxiao Wan, Rui wu, Heying Sun, Danqing Lu Published: Friday, March 27, 2020 Viewed: 2666
Editorial Time for an Alzheimer’s disease cocktail Warren Ladiges Published: Friday, March 27, 2020 Viewed: 2655
Technology Feature QuPath. A new digital imaging tool for geropathology Warren Ladiges, Amanda Lee, Zhou Jiang, Lida Zhu Published: Monday, June 29, 2020 Viewed: 2652
Research Article Mitochondrial-targeted methionine sulfoxide reductase overexpression increases the production of oxidative stress in mitochondria from skeletal muscle Adam Salmon, Arunabh Bhattacharya, Daniel Pulliam, Yuhong Liu Published: Friday, March 27, 2020 Viewed: 2578
Research Article LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression Jianda Dong, Pihong Li, Xiaoyu Pan, Zhouci Zheng, Yihan Sun, Yifan Han Published: Monday, June 29, 2020 Viewed: 2369
Review Guidelines for the Prevention of Coronavirus Pneumonia in Elderly People Wei Ma, Jun Zhao, Gang Xu, Congrui Feng, Yuluo Chen, Feng Liu Published: Monday, June 29, 2020 Viewed: 2339
Model Profile A mouse model of sleep deprived neuropathology to study resilience to Alzheimer’s disease Warren Ladiges, Yan Dou, Jinzi Wu, Lida Zhu, Martin Darvas Published: Monday, June 29, 2020 Viewed: 2293
Review Aging pet cats develop neuropathology similar to human Alzheimer’s disease Warren Ladiges, Jenna Klug, Jessica M. Snyder, Martin Darvas, Denise M. Imai, Molly Church, Caitlin Latimer, C . Dirk Keene Published: Tuesday, September 29, 2020 Viewed: 2284
Editorial Oxidative stress in aging: stayin’ alive? Lisa Flores, Yuji Ikeno Published: Monday, June 29, 2020 Viewed: 2280
Research Article IL-17 regulates the expression of major histocompatibility complex II and VEGF in DLBCL mice on tumor growth Xin Xu, Ting Wei, Weijie Zhong, Zhigang Zhu, Feng Liu, Qingshan Li Published: Monday, June 29, 2020 Viewed: 2130
Review Gastrointestinal Disasters of Cetuximab in the Treatment of Metastatic Colorectal Cancer: Mechanism and its Effect on Prognosis Junfeng Sun, Yue Wu, Haowei Jia, Xinqi Bao, Tianyu Zhu, Ruixin Li, Hongchao Zhao Published: Monday, June 29, 2020 Viewed: 2023
Technology Feature An immune stress test for resilience to aging: Pneumococcal vaccine response Warren Ladiges, Ryan Oveson, Zhou Jiang, Michali Izhak, Kavita Sharma Published: Tuesday, September 29, 2020 Viewed: 1971
Therapeutic Brief The potential of XPO1 inhibitors as a game changer in relapsed/refractory hematologic malignancies Henan Wang, Liang Wang, Jing Yang Published: Monday, June 29, 2020 Viewed: 1961
Editorial Commentary A geropathology approach for identifying therapeutic targets to prevent pathological complications of COVID-19 Warren Ladiges, Yuji Ikeno, Liang Wang, Feng Liu Published: Monday, June 29, 2020 Viewed: 1950
Review Thioredoxin and aging: What have we learned from the survival studies? Lisa Flores, Madeline Roman, Geneva Cunningham, Christie Cheng, Colton Allen, Gene Hubbard, Yidong Bai, Thomas Saunders, Yuji Ikeno Published: Tuesday, September 29, 2020 Viewed: 1945
Research Article Finding prodromal frailty in a community-dwelling healthy older cohort by survey of BDNF or hand grip strength classified by BMI Mitsugu Hachisu, Masahiro Hashizume, Hisashi Kawai, Motonaga Kojima, Yoshinori Fujiwara, Shuichi Obuchi, Mari Kogo, Masayuki Ohbayashi, Noriko Koyama, Miki Takenaka, Kazushige Ihara Published: Tuesday, September 29, 2020 Viewed: 1945
Model Profile A model for studying cutaneous wound healing and resilience to aging: Ear punch biopsy in old mice Warren Ladiges, Zhou Jiang, Jessie Chen, Juan Wang, Ruby Mangalindan, Lida Zhu Published: Tuesday, September 29, 2020 Viewed: 1935
Research Article Anti-tumor effect of pcDNA3.1(-)/rMETase-shUCA1 hyaluronic acid-modified G5 polyamidoamine nanoparticles on gastric cancer Chunying Xie, Zhenxing Huang, Zhaohui Huang, Yanyan Guo, Xue Zhang Published: Monday, June 29, 2020 Viewed: 1885
Review Myocardial Cell Aging in the Elderly Feng Liu, Wenxi Li Published: Tuesday, September 29, 2020 Viewed: 1820
Review The cellular senescence unification model and telomerase therapy: To treat all age-related diseases Steve Liebich Published: Tuesday, September 29, 2020 Viewed: 1748
Editorial Immunotherapy: the blockbuster in cancer treatment Liang Wang Published: Tuesday, September 29, 2020 Viewed: 1704
Therapeutic Brief Short-term oral rapamycin prevents age-related learning impairment in mice Warren Ladiges, Haoyi Lei, Juan Wang, Zhou Jiang Published: Tuesday, September 29, 2020 Viewed: 1692
Geropathology Notes Eosinophilic crystalline pneumonia, an age-related lesion in mice Jenna Klug, Jessica Snyder Published: Thursday, December 31, 2020 Viewed: 1663
Reviewer Acknowledgement 2020 Reviewer Acknowledgment Editorial Office of Aging Pathobiology and Therapeutics Published: Thursday, December 31, 2020 Viewed: 1644
Case Report Coronary artery stenosis regression by long-term standard dose statin therapy in middle-aged and elderly patients: Report and analysis of 31 cases Feng Liu, Zhilei Ren, Chongzhe Yang, Kaihua Huang Published: Tuesday, September 29, 2020 Viewed: 1589
Research Article Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment Warren Ladiges, Amanda Lee, Haoyi Lei, Lida Zhu, Zhou Jiang Published: Thursday, December 31, 2020 Viewed: 1582
Research Article Sex-dependent lifespan extension of ApcMin/+ FAP mice by chronic mTOR inhibition Manish Parihar, Sherry Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Sharp Published: Thursday, December 31, 2020 Viewed: 1563
Model Profile Neutrophil response to cyclophosphamide predicts resilience to age-related learning impairment Lida Zhu, Warren Ladiges, Katie Nickel, Marianne Bjorner Published: Thursday, December 31, 2020 Viewed: 1545
Therapeutic Brief Denosumab for the treatment of osteoporosis Shyh Poh Teo Published: Tuesday, September 29, 2020 Viewed: 1542
Research Article miR-181c inhibits prostatic epithelial cell proliferation caused by chronic non-bacterial prostatitis through down-regulating COX-2 Xiang Ding, Xu Xu, Yuhua Huang, Jianquan Hou, Jinxing Lv Published: Thursday, December 31, 2020 Viewed: 1472
Review Application and research progress of BCL2 inhibitors in elderly patients with hematologic malignancies Liang Wang, Yufan Wang Published: Thursday, December 31, 2020 Viewed: 1463
Letter to Editor Optimal induction treatment regimens for extranodal NK/T-cell lymphoma: lessons learned, challenges, and proposals Liang Wang, Jing Yang, Ruiying Fu, Xindi Liu, Liqiang Wei Published: Thursday, December 31, 2020 Viewed: 1462
Case Report Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study Eleonora Duregon, Rafael de Cabo, Camila Vieira Ligo Teixeira, Dushani L. Palliyaguru, Annamaria L. Rudderow, Victoria Hoffmann, Michel Bernier, Nathan L. Price, Simonetta Camandola Published: Thursday, December 31, 2020 Viewed: 1440
Case Report Castleman disease with rapidly progressive pemphigus: case report Liang Wang, Ruiying Fu, Yingzhi He Published: Thursday, December 31, 2020 Viewed: 1434
Therapeutic Brief Physical performance is enhanced in old mice fed a short term diet medicated with rapamycin, acarbose, and phenylbutyrate Warren Ladiges, Megan Ellis, Zhou Jiang Published: Monday, March 29, 2021 Viewed: 1423
Editorial Progress in drug treatment of elderly chronic heart failure Feng Liu, Siting Zhang Published: Thursday, December 31, 2020 Viewed: 1365
Research Article Thioredoxin down-regulation in the cytosol in thioredoxin 2 transgenic mice did not have beneficial effects to extend lifespan in male C57BL/6 mice Lisa Flores, Madeline Roman, Geneva Cunningham, Christie Cheng, Colton Allen, Yidong Bai, Gene Hubbard, Yuji Ikeno Published: Thursday, December 31, 2020 Viewed: 1343
Review Recent advances in the genetic association between osteoporotic fracture and sarcopenia Qiaocong Chen, Huiling Lou, Cheng Peng Published: Monday, March 29, 2021 Viewed: 1263
Geropathology Notes Hepatic steatosis, a lesion reported in captive aged common marmosets Sebastian Carrasco, Olga Franco-Mahecha Published: Monday, March 29, 2021 Viewed: 1232
Editorial Harnessing the heterogeneity of aging Warren Ladiges Published: Monday, March 29, 2021 Viewed: 1215
Letter to Editor Arthritis as an adverse event of special interest post COVID-19 vaccine implementation Shyh Poh Teo Published: Monday, March 29, 2021 Viewed: 1193
Mini Review Drug nanotargeting for treatment of neurodegeneration and aging Joseph D'Arrigo Published: Tuesday, June 29, 2021 Viewed: 1094
Case Report Cardiac arrest in an older male patient treated with flecainide for atrial fibrillation Tiziana Ciarambino, Rosario Bottone, Gennaro Sansone, Mauro Giordano Published: Tuesday, June 29, 2021 Viewed: 829
Therapeutic Brief Gam-COVID-Vac (Sputnik V): a heterologous adenoviral vector-based COVID-19 vaccine Shyh Poh Teo, Sanny Zi Lung Choo Published: Tuesday, June 29, 2021 Viewed: 803
Case Report Irreversible effects of anticholinergic withdrawal in the elderly: a case report Charisse Chehovich, Claudia Lee, Tammie Lee Demler Published: Tuesday, June 29, 2021 Viewed: 646
Editorial Thioredoxin – a magic bullet or a double-edged sword for mammalian aging? Yuji Ikeno Published: Tuesday, June 29, 2021 Viewed: 579
Therapeutic Brief The antidiabetic drug acarbose suppresses age-related lesions in C57BL/6 mice in an organ dependent manner Zhou Jiang, Sneh Gupta, Warren Ladiges Published: Tuesday, June 29, 2021 Viewed: 573
Case Report Older female relatives of Covid-19 patients have an un-satisfactory perception of emergency room performance by clinical staff Tiziana Ciarambino, Luigia Palmiero, Rosario Bottone, Federico Schettini, Luigi Elio Adinolfi, Mauro Giordano Published: Tuesday, June 29, 2021 Viewed: 553
Case Report A fornix infarction causing post-operative anterograde amnesia Shyh Poh Teo Published: Tuesday, June 29, 2021 Viewed: 552
Editorial Commentary Precision aging. Human lifespan has intrinsic limits but measurable outcomes Warren Ladiges Published: Tuesday, June 29, 2021 Viewed: 548
Editorial Chimeric Antigen Receptor T cell Therapy in Cancer: Advances and Challenges Liang Wang Published: Thursday, August 26, 2021 Viewed: 117


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