Aging Pathobiology and Therapeutics

Aging Pathobiology and Therapeutics (APT, Online ISSN 2690-1803) is an open access, peer-reviewed, interdisciplinary journal available online. The journal quarterly publishes research articles, reviews, editorials, case reports, opinions, letters, abstracts and drug therapeutic brief relating to research on Aging related diseases. The journal aims to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of Aging Pathobiology and Therapeutics research. Scholars from the disciplines of geriatrics, gerontology, physiology, pathology, pharmacology, toxicology, biology, neuropsychology, psychology, nursing, epidemiology, and genetics are encouraged to contribute articles to the journal.

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Reviewer Acknowledgement 2020 Reviewer Acknowledgment Editorial Office of Aging Pathobiology and Therapeutics Published: Thursday, December 31, 2020

Editorial Progress in drug treatment of elderly chronic heart failure Feng Liu, Siting Zhang Published: Thursday, December 31, 2020

Research Article Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment Warren Ladiges, Amanda Lee, Haoyi Lei, Lida Zhu, Zhou Jiang Published: Thursday, December 31, 2020

Case Report Castleman disease with rapidly progressive pemphigus: case report Liang Wang, Ruiying Fu, Yingzhi He Published: Thursday, December 31, 2020

Case Report Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study Eleonora Duregon, Rafael de Cabo, Camila Vieira Ligo Teixeira, Dushani L. Palliyaguru, Annamaria L. Rudderow, Victoria Hoffmann, Michel Bernier, Nathan L. Price, Simonetta Camandola Published: Thursday, December 31, 2020

Research Article miR-181c inhibits prostatic epithelial cell proliferation caused by chronic non-bacterial prostatitis through down-regulating COX-2 Xiang Ding, Xu Xu, Yuhua Huang, Jianquan Hou, Jinxing Lv Published: Thursday, December 31, 2020

Model Profile Neutrophil response to cyclophosphamide predicts resilience to age-related learning impairment Lida Zhu, Warren Ladiges, Katie Nickel, Marianne Bjorner Published: Thursday, December 31, 2020

Letter to Editor Optimal induction treatment regimens for extranodal NK/T-cell lymphoma: lessons learned, challenges, and proposals Liang Wang, Jing Yang, Ruiying Fu, Xindi Liu, Liqiang Wei Published: Thursday, December 31, 2020

Geropathology Notes Eosinophilic crystalline pneumonia, an age-related lesion in mice Jenna Klug, Jessica Snyder Published: Thursday, December 31, 2020

Review Application and research progress of BCL2 inhibitors in elderly patients with hematologic malignancies Liang Wang, Yufan Wang Published: Thursday, December 31, 2020

Research Article Thioredoxin down-regulation in the cytosol in thioredoxin 2 transgenic mice did not have beneficial effects to extend lifespan in male C57BL/6 mice Lisa Flores, Madeline Roman, Geneva Cunningham, Christie Cheng, Colton Allen, Yidong Bai, Gene Hubbard, Yuji Ikeno Published: Thursday, December 31, 2020

Research Article Sex-dependent lifespan extension of ApcMin/+ FAP mice by chronic mTOR inhibition Manish Parihar, Sherry Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Sharp Published: Thursday, December 31, 2020

Technology Feature An immune stress test for resilience to aging: Pneumococcal vaccine response Warren Ladiges, Ryan Oveson, Zhou Jiang, Michali Izhak, Kavita Sharma Published: Tuesday, September 29, 2020

Model Profile A model for studying cutaneous wound healing and resilience to aging: Ear punch biopsy in old mice Warren Ladiges, Zhou Jiang, Jessie Chen, Juan Wang, Ruby Mangalindan, Lida Zhu Published: Tuesday, September 29, 2020

Therapeutic Brief Short-term oral rapamycin prevents age-related learning impairment in mice Warren Ladiges, Haoyi Lei, Juan Wang, Zhou Jiang Published: Tuesday, September 29, 2020

Annoucement More>>

Thursday, December 31, 2020

The latest issue has published and expects your visit!

Vol 2, No 4 (2020): Aging Pathobiology and Therapeutics is the latest issue of Aging Pathobiology and Therapeutics. Now it has published.

Wednesday, December 30, 2020

Journal (Aging Pathobiology and Therapeutics) Calls for Editorial Board Members

Editorial Board plays an important role in maintaining the quality and promote the development of a journal. The term of an Editorial Board member is 3 years with an option to be renewed.

Wednesday, December 30, 2020

Invitation to submit manuscript to Aging Pathobiology and Therapeutics

We kindly invite you to submit a manuscript for publication in Aging Pathobiology and Therapeutics (APT). The academic articles in the journal will be published online, through Open Access mode, and will be available worldwide freely and immediately, without restrictions.

Tuesday, June 30, 2020

New Manuscript Format Introduction - Model Profile and Technology Feature

Vol 2, No 2 (2020):Aging Pathobiology and Therapeutics has added two new manuscript formats - Model Profile and Technology Feature.

Journal Highlight