Aging Pathobiology and Therapeutics

Aging Pathobiology and Therapeutics (APT, Online ISSN 2690-1803) is open access, peer-reviewed, interdisciplinary journal available online. The journal quarterly publishes research articles, reviews, editorials, case reports, opinions, letters, abstracts, and therapeutic drug briefs relating to research on the pathobiology of aging and age-related diseases. The journal aims to provide a platform for scientists and academicians worldwide to promote, share, and discuss various new issues and developments in different areas of the pathobiology of aging and age-related diseases. Scholars from the disciplines of geriatrics, gerontology, physiology, pathology, pharmacology, toxicology, biology, neuropsychology, psychology, nursing, epidemiology, and genetics are encouraged to contribute articles to the journal.

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Review Cardiovascular aging in patients with chronic kidney disease: pathogenesis and potential therapeutics Safa Alkhayyat, Mohamed Abdalbary, Zahraa Alhoori Published: Thursday, September 28, 2023

Editorial Physical resilience is a predictor of healthy aging Warren Ladiges Published: Thursday, September 28, 2023

Review The role of immune aging in giant cell arteritis Patricia Harkins, Sharon Cowley, Robert Harrington, David Kane, Richard Conway Published: Thursday, September 28, 2023

Research Article Older-aged C57BL/6 mice fed a diet high in saturated fat and sucrose for ten months show decreased resilience to aging Chloe N Johnson, Lida Zhu, Ruby Mangalindan, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, David J. Marcinek, Peter Rabinovitch, Warren Ladiges Published: Thursday, September 28, 2023

Mini Review Biobased nanoemulsions for targeted drug delivery to treat dementia and aging Joseph S. D'Arrigo Published: Thursday, September 28, 2023

Mini Review Role of fibro-adipogenic progenitors in skeletal muscle aging Renwen Wan, Hanli Zhang, Shan Liu, Chunmeng Jiao, Hui Chen, Zhiwen Luo, Xiliang Shang Published: Wednesday, June 28, 2023

Review Nrf2 participates in progression of osteoarthritis through modulating redox balance Yueqi Chen, Zihan Deng, Chuan Yang Published: Thursday, September 28, 2023

Research Article Targeted regulation of senescence-associated secretory phenotype with an aptamer-conjugated activatable senomorphic Yanlan Liu, Yuqi Xie, Jili Li, Pingyu Wu, Linlin Wang, Donghui Hong, Jian Wang Published: Wednesday, June 28, 2023

Commentary In vitro geroscience. Screening anti-aging drug combinations for neurodegenerative diseases Warren Ladiges, Soroosh Fatemi, Joo Young Park Published: Wednesday, June 28, 2023

Case Report The case of a geriatric female experiencing frequent falls and epileptic seizures during long-term low-dose clozapine and extended-release bupropion treatment Charisse Dzierba, Claudia Lee, Tammie Lee Demler Published: Wednesday, June 28, 2023

Editorial Ethylnitrosourea-induced gliomas: a song in the attic? Yuji Ikeno Published: Wednesday, June 28, 2023

Research Article Additional polgD257A mutation (mutator) does not influence dopaminergic neurodegeneration in aged parkin-deficient mice Xin-Ran Zhu, David Mrohs, Max Rybarski, Michael Andriske, Pauline Bohne, Melanie D. Mark, Hermann Lübbert Published: Tuesday, May 23, 2023

Review Age effect on mesenchymal stem cell properties: A concise review Tsz Kin Ng, Chong-Bo Chen, Xin Bin, Yuqiang Huang, Herman S. Cheung Published: Tuesday, May 23, 2023

Review Senescence of mesenchymal stem cells: implications in extracellular vesicles, miRNAs and their functional and therapeutic potentials Guangqian Zhou, Liangge He, Mingzhu Li, Zhen Liu, Arshad Ahmed Padhiar Published: Thursday, September 28, 2023

Review Influence of metformin on age-related macular degeneration Albert J Augustin, Jenny Atorf Published: Tuesday, May 23, 2023

Annoucement More>>

Thursday, September 28, 2023

The latest issue has been published!

September | Vol 5, No 3 (2023) has been published, welcome to read and share!

Friday, May 19, 2023

APT has been included in Scopus!

The Scopus Content Selection & Advisory Board (CSAB) has approved APT for coverage.

Friday, August 12, 2022

APT added a new column - Interview

Scientists in the field of aging research are cordially invited to participate in this "Interview" column.

Wednesday, August 10, 2022

The Aged Rodent Tissue Bank is a cost-effective resource for aging research---a note of scientific interest

The National Institute on Aging (NIA), one of the institutes of the National Institutes of Health USA, has long provided biological resources to the biogerontology community to foster research on aging.

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