Biomarkers for prognostic stratification in chronic heart failure in older patients

Abstract

Chronic heart failure (CHF) is a common complication of cardiovascular diseases in older adults. It has complex pathogenesis and different biomarkers to assess this process. Only  natriuretic peptides are recommended in current guidelines to diagnose CHF. The role of other markers remains unclear. Some studies showed prognostic value of such markers as sST2, galectin-3, troponins. We need further investigations to find markers for assessing prognosis in older adults with CHF to choose the optimal treatment strategy for them and prolong their lives.

Keywords: Chronic heart failure, NT-proBNP, sST2, galectin-3, troponins, older patients.