Aging Pathobiology and Therapeutics

Aging Pathobiology and Therapeutics (APT, Online ISSN 2690-1803) is an open access, peer-reviewed, interdisciplinary journal available online. The journal quarterly publishes research articles, reviews, editorials, case reports, opinions, letters, abstracts and drug therapeutic brief relating to research on Aging related diseases. The journal aims to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of Aging Pathobiology and Therapeutics research. Scholars from the disciplines of geriatrics, gerontology, physiology, pathology, pharmacology, toxicology, biology, neuropsychology, psychology, nursing, epidemiology, and genetics are encouraged to contribute articles to the journal.

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Most Viewed Articles

Research Article Highly expressed ribosomal protein L34 predicts poor prognosis in acute myeloid leukemia and could be a potential therapy target Liang Wang, Jing Yang, Henan Wang, Weida Wang, Xiaojie Liang Published: Friday, March 27, 2020

Editorial Time for an Alzheimer’s disease cocktail Warren Ladiges Published: Friday, March 27, 2020

Review Development of a Geropathology Grading Platform for nonhuman primates Warren Ladiges, Katie Olstad, Denise Imai, Rebekah Keesler, Rachel Reader, John Morrison, Jeffery Roberts, John Capitanio, Elizabeth Didier, Marcelo Kuroda, Heather Simmons, Shabnam Salimi, Julie Mattison, Yuji Ikeno Published: Friday, March 27, 2020

Abstract Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging Warren Ladiges, Yuji Ikeno, Liang Wang Published: Friday, March 27, 2020

Therapeutic Brief The potential of GHK as an anti-aging peptide Warren Ladiges, Yan Dou, Amanda Lee, Lida Zhu, John Morton Published: Friday, March 27, 2020

Research Article Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice Madeline Roman, Lisa Flores, Geneva Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Thomas Saunders, Yuji Ikeno Published: Friday, March 27, 2020

Research Article Down-regulation of miR-181a promotes microglial M1 polarization through increasing expression of NDRG2 Bo Zhou, Yali Niu, Chunxiao Wan, Rui wu, Heying Sun, Danqing Lu Published: Friday, March 27, 2020

Research Article Mitochondrial-targeted methionine sulfoxide reductase overexpression increases the production of oxidative stress in mitochondria from skeletal muscle Adam Salmon, Arunabh Bhattacharya, Daniel Pulliam, Yuhong Liu Published: Friday, March 27, 2020

Research Article Pioglitazone up-regulates MALAT1 and promotes the proliferation of endothelial progenitor cells through increasing c-Myc expression in type 2 diabetes mellitus Xiaoxu Yang, Chen Hu, Yan Sun Published: Friday, March 27, 2020

Research Article Sleep-deprived cognitive impairment in aging mice is alleviated by rapamycin Warren Ladiges, Kishore Mukherjee, Amanda Lee, Lida Zhu, Martin Darvas Published: Monday, December 30, 2019

Research Article Interfering with miR-24 alleviates rotenone-induced dopaminergic neuron injury via enhancing autophagy by upregulating DJ-1 Fengrui Li, Biao Ge, Hairong Wu, Dan Shao, Shulin Li Published: Monday, December 30, 2019

Research Article MicroRNA-152 suppresses cell proliferation and tumor growth of bladder cancer by targeting KLF5 and MKK7 Liangliang Wang, Yu Hui, Yuhua Huang, Xiang Ding Published: Monday, December 30, 2019

Review The rationale for testing drug combinations in aging intervention studies Kavita Sharma, Juan Wang, Zhou Jiang, Jenna Klug, Martin Darvas, Denise Imai, Timothy Snider, Laura Niedernhofer, Warren Ladiges Published: Monday, December 30, 2019

Case Report Drug-Induced Hemolytic Crisis During Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma: A Rare Hematologic Adverse Reaction Xin Wen, Liang Wang, Yingzhi He, Shan Wang Published: Monday, December 30, 2019

Annoucement More>>

Friday, March 27, 2020

The latest issue has published and expects your visit!

Vol 2, No 1 (2020): Aging Pathobiology and Therapeutics is the latest issue of Aging Pathobiology and Therapeutics. Now it has published!

Friday, March 27, 2020

Abstracts from the 2019 Barshop Conference on Aging!

Abstracts from the 2019 Barshop Conference on Aging has been published !

Friday, March 20, 2020

New Journal (Aging Pathobiology and Therapeutics) Calls for Editorial Board Members

Editorial Board plays an important role in maintaining the quality and promote the development of a journal. The term of an Editorial Board member is 3 years with an option to be renewed.

Friday, March 20, 2020

Invitation to submit manuscript to Aging Pathobiology and Therapeutics

We kindly invite you to submit a manuscript for publication in Aging Pathobiology and Therapeutics (APT). The academic articles in the journal will be published online, through Open Access mode, and will be available worldwide freely and immediately, without restrictions.

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