Progress on the study of fibroblast growth factors as novel therapeutics in post-stroke cognitive impairment | Li | Aging Pathobiology and Therapeutics

Progress on the study of fibroblast growth factors as novel therapeutics in post-stroke cognitive impairment

Mengqi Li, Hong Fan

Abstract


Post-stroke cognitive impairment (PSCI) is one of the most common complications after stroke, which severely affects the daily life abilities and social function of patients. Fibroblast growth factor (FGF), as a regulator of homeostasis, participates in the regulation of cell metabolism and hormone secretion, and can increase cerebral blood flow and promote nerve repair which improves PSCI. Here, we will conduct a review on the typing, characteristics, and mechanism of action of FGF to further understand its function and mechanism in PSCI.

Keywords: Fibroblast growth factor, cognitive impairment, stroke




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