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Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice

Disruption of metabolic and bioenergetic homeostasis related to mitochondrial dysfunction is a key driver of aging biology

The critical role of macrophages in ovarian cancer treatment

The occurrence of and poor prognosis associated with ovarian cancer (OC) pose a serious threat to the health of middle-aged and elderly women.

Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older

Aging, which is accompanied by loss of muscle mass, strength, and function, may contribute to the development of frailty

Nasal type extranodal natural killer/T-cell lymphomaassociated hemophagocytic lymphohistiocytosis: a Case report and lit

Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome in which a large number of inflammatory cytokines, such

Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging

Decades of aging research established several well-characterized theories of aging, yet as the studies often focus on di

Resilience to aging is a heterogeneous characteristic defined by physical stressors

Physical resilience, the capacity to respond to and recover from a stressful event, declines with advancing age. Individ

Geropathology. An inside view of biological aging

The geropathology concept assumes all age-related lesions are relevant, which allows the ability to grade each lesion in

Clear cell sarcoma: 20 years of experience at Instituto Nacional de Enfermedades Neoplasicas (INEN)

Clear cell sarcoma (CCS) of soft tissue is a rare disease with a high risk of metastasis to regional lymph nodes and di

The rare patient with infrainguinal stent restenosis a complication: Atherectomy device fracture

Excisional atherectomy alone or followed by balloon angioplasty in patients with infra-inguinal peripheral artery diseas

Focused ultrasound surgery in gynecology – a call to validate a new surgical approach

Ultrasound-guided HIFU (USgHIFU) ablation is now a new non-invasive surgical procedure that developed rapidly in China,

Latest Articles

Interview Towards clinical translation of biomarkers and therapies targeting autolysosomal acidification dysfunction in neuroinflammation and neurodegeneration—an interview with Prof. David Rubinsztein Chih Hung Lo Published: Sunday, September 29, 2024

Research Article Two-sample mendelian randomization study: vitamin D levels and chronic kidney disease in the elderly population Ling Xiao, Kaiping Luo, Honghong Zou Published: Sunday, September 29, 2024

Letter to Editor Metabolic dysfunction-associated steatotic liver disease of older people Chieh Chen, Da-Ming Liao Published: Friday, August 16, 2024

Case Report Robot-assisted pyeloplasty and pyelolithotomy in patient with osteogenesis imperfecta Marco Rinaldi, Carmine Franzese, Jeanlou Collavino, Maria Abbinante, Sasha Sekulovic, Gioacchino De Giorgi, Fabio Traunero, Gianluca Giannarini, Alessandro Crestani Published: Monday, July 29, 2024

Brief Correspondence Neoadjuvant chemotherapy should only be considered in patients with cT3-T4a muscle-invasive bladder cancer Sytse van Beek, Noor van Ginkel, Joost L. Boormans, André N. Vis, Dutch Cystectomy Snapshot Research Group Published: Thursday, September 5, 2024

Original Article The effects of 5-ARIs on prostate volume in patients with or without heart failure and benign prostate hyperplasia: prospective, comparative study Denis Krakhotkin, Volodymyr A. Chernylovskyi, Francesco Greco, Aly M Abdel-Karim, Ali Serdar Gözen, Anastasia G. Korplyakova, Nikolay Yu. Iglovikov Published: Thursday, July 18, 2024

Editorial The use of 5 alpha-reductase in the era of minimally invasive surgical therapies (MISTs): Is it still valuable? Francesco Greco, Luigi Domanico Published: Wednesday, August 7, 2024

Interview Minimally invasive surgical therapies (MISTs) for benign prostatic hyperplasia: current insights and future directions—Interview with Prof. Francesco Greco Carlotta Nedbal Published: Monday, August 19, 2024

Research Article Technical development of senescence-associated β-galactosidase staining in frozen kidney tissue of Sprague Dawley rat Yuji Ikeno, Ganga Tandukar, Lisa C. Flores, Colton Allen, Yidong Bai Published: Tuesday, September 24, 2024

Editorial The promise of adult neurogenesis for treating and preventing chronic neurodegenerative diseases Warren Ladiges, Gerald Yu Liao Published: Friday, September 13, 2024

Research Article Effect of Pilates versus resistance training on physical fitness in older adults Manisha Rathi, Khushboo Muthiyan, Reema Joshi, Preeti Gazbare Published: Thursday, September 12, 2024

Research Article Behavioral and neuropathological features of Alzheimer’s disease are attenuated in 5xFAD mice treated with intranasal GHK peptide Matthew Tucker, Gerald Liao, Joo Young Park, Manuela Rosenfeld, Jackson Wezeman, Ruby Mangalindan, Dan Ratner, Martin Darvas, Warren Ladiges, Addison Keely Published: Monday, August 26, 2024

Interview A natural way for a healthier lifestyle—an interview with Prof. Stephen C. Bondy Alessandro Bitto Published: Friday, August 16, 2024

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