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Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice

Disruption of metabolic and bioenergetic homeostasis related to mitochondrial dysfunction is a key driver of aging biology

The critical role of macrophages in ovarian cancer treatment

The occurrence of and poor prognosis associated with ovarian cancer (OC) pose a serious threat to the health of middle-aged and elderly women.

Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older

Aging, which is accompanied by loss of muscle mass, strength, and function, may contribute to the development of frailty

Nasal type extranodal natural killer/T-cell lymphomaassociated hemophagocytic lymphohistiocytosis: a Case report and lit

Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome in which a large number of inflammatory cytokines, such

Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging

Decades of aging research established several well-characterized theories of aging, yet as the studies often focus on di

Resilience to aging is a heterogeneous characteristic defined by physical stressors

Physical resilience, the capacity to respond to and recover from a stressful event, declines with advancing age. Individ

Geropathology. An inside view of biological aging

The geropathology concept assumes all age-related lesions are relevant, which allows the ability to grade each lesion in

Clear cell sarcoma: 20 years of experience at Instituto Nacional de Enfermedades Neoplasicas (INEN)

Clear cell sarcoma (CCS) of soft tissue is a rare disease with a high risk of metastasis to regional lymph nodes and di

The rare patient with infrainguinal stent restenosis a complication: Atherectomy device fracture

Excisional atherectomy alone or followed by balloon angioplasty in patients with infra-inguinal peripheral artery diseas

Focused ultrasound surgery in gynecology – a call to validate a new surgical approach

Ultrasound-guided HIFU (USgHIFU) ablation is now a new non-invasive surgical procedure that developed rapidly in China,

Latest Articles

Model Profile Cartilage organoid model of osteoarthritis to study aging-related diseases Guangxuan Yan, Yongxiong He, Zhiqiang Shi, Yuan Li, Kai Tao, Jun Fan, Qiankun Zhu, Heng Wang, Aitao Wang, Yongchao Li Published: Friday, June 27, 2025

Letter to Editor The role of epigenetics in cognitive aging: mechanisms, interventions, and future directions Abdullah Noman, Pranab Sharma, Himanshu Sharma Published: Friday, June 27, 2025

Research Article Effects of structured group reminiscence in sports and non-sports environments on cognitive empowerment and optimism in older adults: a quasi-experimental study Bahador Azizi, Amin Azimkhani, Mohammad Khazaei, Saleh Moazam, Nazli Ilchizadeh, Katarzyna Dzioban Published: Friday, June 27, 2025

Research Article The estimation of the clinical status of the residents in a geriatric health service facility in Japan. Toyoki Maeda Published: Friday, June 27, 2025

Commentary Biomarkers for prognostic stratification in chronic heart failure in older patients Anton R. Kiselev, Kseniya D. Dorogoykina Published: Friday, June 27, 2025

Research Article From plants to potential therapeutics: exploring neuroprotective properties against Alzheimer’s disease through molecular docking and MD simulations Ashwani Kumar, Shubham Kumar, Aanchal Gupta, Chirag N. Patel, Vikas Kumar Published: Friday, June 27, 2025

Review Inflammaging and microbiota: the intersection of aging, inflammation, and gut health Harish Rangareddy, Jessica Fryer, Achal Shetty, Hayfa Rajhi Published: Friday, June 27, 2025

Editorial The neuropathology of aging and Alzheimer’s disease in domestic cats Warren Ladiges, Ankita Sharma Published: Friday, June 27, 2025

Original Article Office-based ureteral stent placement and stent exchange using mild sedation, local anesthesia, and no fluoroscopic guidance: safety, efficacy, and feasibility Anthony Pamatmat, Nitan Sharma, Scott Quarrier, Rajat Jain Published: Friday, June 27, 2025

Original Article Endoscopic lithotripsy in patients with asymptomatic bacteriuria Sergey Sukhikh, Vigen Malkhasyan, Nariman Gadzhiev, Egor Maltsev, Dmitry Yu. Pushkar, Islam Z. Kindarov Published: Friday, June 27, 2025

Original Article An original instrument for diagnosing inflammation of the paraurethral glands in women Nikolai Iglovikov, Pavel Kislitsyn, Kirill Maltsev, Vladimir Protoshchak, Denis Krakhotkin Published: Friday, June 27, 2025

Review Laparoscopic versus robotic nephrectomy: clinical outcomes, cost-effectiveness, and future innovations in minimally invasive renal surgery Shirin Razdan, Ali Fathollahi, Sanjay Razdan Published: Friday, June 27, 2025

Review Flexible and navigable ureteral access sheath (FANS-UAS): a narrative literature review Luis Enrique Ortega Polledo, Álvaro Serrano Pascual, Eduardo J. García Rico, Miguel Ángel Ruiz León, Geo F.J. Bianchini Hernández, Alejandro Sánchez Pellejero, Ángeles Sanchís Bonet, Laura Ibañez Vázquez, Paula Mata Deniz, Isabel Galante Romo, Juan Gómez Rivas, Sergio Alonso y Gregorio, Jesús Moreno Sierra Published: Friday, June 27, 2025

Research Article Integrative bioinformatics and molecular docking unveil multi-target therapeutic mechanisms of Coptidis Rhizoma (CR) against Lewy body dementia (LBD): an in-silico approach Pranab Dev Sharma, Abdullah Al Noman Published: Friday, June 6, 2025

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