A half-century history of aging research in San Antonio

Abstract

Since the biology of aging program started in 1975, the aging research group/Barshop Institute in San Antonio has been one of the front runners of aging research. Over the last half-century, aging research has rapidly advanced through examining the aging pathobiology and anti-aging effects of calorie restriction, genetic and pharmacological interventions, and translational and clinical studies. These developments and evolution of aging research are entering a new frontier aimed to uncover the complexity of aging processes and discover the anti-aging (preventive and/or therapeutic) measures for humans using cutting-edge technologies (multi-omics approaches and artificial intelligence/computational biology analyses).

The San Antonio aging research group and the Barshop Institute will continue to serve as one of the premier institutes for aging research under the strong leadership of the former and current directors to carry on Dr. Edward Masoro’s legacy.

Keywords: Calorie restriction, genetic intervention, pharmacological intervention, translational research, aging