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Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice

Disruption of metabolic and bioenergetic homeostasis related to mitochondrial dysfunction is a key driver of aging biology

The critical role of macrophages in ovarian cancer treatment

The occurrence of and poor prognosis associated with ovarian cancer (OC) pose a serious threat to the health of middle-aged and elderly women.

Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older

Aging, which is accompanied by loss of muscle mass, strength, and function, may contribute to the development of frailty

Nasal type extranodal natural killer/T-cell lymphomaassociated hemophagocytic lymphohistiocytosis: a Case report and lit

Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome in which a large number of inflammatory cytokines, such

Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging

Decades of aging research established several well-characterized theories of aging, yet as the studies often focus on di

Resilience to aging is a heterogeneous characteristic defined by physical stressors

Physical resilience, the capacity to respond to and recover from a stressful event, declines with advancing age. Individ

Geropathology. An inside view of biological aging

The geropathology concept assumes all age-related lesions are relevant, which allows the ability to grade each lesion in

Clear cell sarcoma: 20 years of experience at Instituto Nacional de Enfermedades Neoplasicas (INEN)

Clear cell sarcoma (CCS) of soft tissue is a rare disease with a high risk of metastasis to regional lymph nodes and di

The rare patient with infrainguinal stent restenosis a complication: Atherectomy device fracture

Excisional atherectomy alone or followed by balloon angioplasty in patients with infra-inguinal peripheral artery diseas

Focused ultrasound surgery in gynecology – a call to validate a new surgical approach

Ultrasound-guided HIFU (USgHIFU) ablation is now a new non-invasive surgical procedure that developed rapidly in China,

Latest Articles

Commentary Sarcopenia beyond muscle: a public health challenge Maria Júlia dos Reis Caetano, Letícia Victória Silva Santos, Gerlane Henriques dos Santos, Ester de Sousa Andrade, Mateus Yan Tavares Aragão, Pedro Henrique Fidelis Barboza, Jarbelle Gomes da Silva, Thamyres Andressa Feitosa Medeiros, Weslley Barbosa Sales Published: Thursday, September 24, 2026

Review Development of dietary supplements to eliminate the atherogenicity of low-density lipoprotein Tatyana Kovyanova, Vasily Karagodin, Daria Borodko, Ulyana Rozhkova, Stanislav Antonov, Aleksandra Utkina, Galina Chizhikova Published: Friday, September 11, 2026

Review Molecular and cellular mechanisms underlying Alzheimer’s disease: an integrated review Mohammad Faraz Tavili, Hussein A. Ghanimi, Hussein A. Ghanimi, Arash Abdolmaleki, Maedeh Naghizadeh Published: Thursday, September 10, 2026

Commentary The cricket brain: a tractable system for decoding neural aging Gerald Yu Liao, Ariana Rhim, Jackson Wezeman, Warren Ladiges Published: Thursday, September 10, 2026

Research Article Development of an organotypic brain slice culture model for testing resilience to aging using tissues collected from geriatric mice Addison Keely, Jackson Wezeman, Savanna Roberts, Sonali Bhana, Warren Ladiges Published: Thursday, September 10, 2026

Editorial The price and promise of robotic surgery: are we over-prioritizing technology? Gerard Hennery Published: Monday, August 31, 2026

Commentary Rethinking sarcopenia screening in middle age—The 2025 AWGS consensus and its implications for cognitive health Chieh Chen, Da-Ming Liao Published: Friday, August 28, 2026

Review Neuroinflammation across neurodegenerative diseases: an aging-conditioned convergence–divergence framework for precision neuroimmunology Mohammad Harun-Ur-Rashid, Israt Jahan Published: Thursday, August 27, 2026

Commentary Aging and memory: a personal perspective Fergus Craik Published: Thursday, August 27, 2026

Review Neuroinflammation in diabetes: from pathophysiological mechanisms to therapeutic opportunities Alma Lomeli-Lepe, Dulce Silva-Silverio, Mónica Ureña-Guerrero, Silvia Josefina López-Pérez Published: Tuesday, August 25, 2026

Mini Review Countering oxysterol-driven neurodegeneration: diosgenin as a privileged steroidal scaffold for novel Alzheimer’s disease therapeutics Sarvesh Sabarathinam Published: Tuesday, June 30, 2026

Review Senotherapeutic potential of Mediterranean diet-derived bioactives in healthy aging and frailty Sedat Arslan Published: Tuesday, June 30, 2026

Editorial Brain iron in ageing: Pixels to pathways Thomas Welton Published: Tuesday, June 30, 2026

Review Robot-assisted simple prostatectomy versus laparoscopic simple prostatectomy: a narrative review of the literature and the state of art Carlos Domingo-Latorre, Alejandro Garcia-Segui, Marco Ferrández-Jiménez, Andrea Albertus-Bofarull, José Lorenzo-González Published: Tuesday, June 30, 2026

Review Contemporary surgical management of urolithiasis: a narrative review Alberto Zambudio Munuera, Irene Millán Ramos, Patricia Rodríguez Parras, Ana Morales Martinez, María Teresa Melgarejo-Segura, Francisco Gutiérrez-Tejero, Miguel Arrabal-Martín, Miguel Ángel Arrabal Polo Published: Tuesday, June 30, 2026

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