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Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice

Disruption of metabolic and bioenergetic homeostasis related to mitochondrial dysfunction is a key driver of aging biology

The critical role of macrophages in ovarian cancer treatment

The occurrence of and poor prognosis associated with ovarian cancer (OC) pose a serious threat to the health of middle-aged and elderly women.

Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older

Aging, which is accompanied by loss of muscle mass, strength, and function, may contribute to the development of frailty

Nasal type extranodal natural killer/T-cell lymphomaassociated hemophagocytic lymphohistiocytosis: a Case report and lit

Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome in which a large number of inflammatory cytokines, such

Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging

Decades of aging research established several well-characterized theories of aging, yet as the studies often focus on di

Resilience to aging is a heterogeneous characteristic defined by physical stressors

Physical resilience, the capacity to respond to and recover from a stressful event, declines with advancing age. Individ

Geropathology. An inside view of biological aging

The geropathology concept assumes all age-related lesions are relevant, which allows the ability to grade each lesion in

Clear cell sarcoma: 20 years of experience at Instituto Nacional de Enfermedades Neoplasicas (INEN)

Clear cell sarcoma (CCS) of soft tissue is a rare disease with a high risk of metastasis to regional lymph nodes and di

The rare patient with infrainguinal stent restenosis a complication: Atherectomy device fracture

Excisional atherectomy alone or followed by balloon angioplasty in patients with infra-inguinal peripheral artery diseas

Focused ultrasound surgery in gynecology – a call to validate a new surgical approach

Ultrasound-guided HIFU (USgHIFU) ablation is now a new non-invasive surgical procedure that developed rapidly in China,

Latest Articles

Commentary L-Fucose is a promising gerotherapeutic drug Warren Ladiges, Jackson Wezeman, Addison Keely Published: Friday, October 31, 2025

Research Article Dysregulation of Nrf2/ARE pathway and mitochondrial DNA damage in aging and Alzheimer’s-associated cognitive decline Polina I. Babenkova, Veronika V. Nesterova, Arina D. Tsvetkova, Anna A. Eremina, Artem P. Gureev, Vera A. Kryukova, Irina S. Sadovnikova Published: Thursday, October 23, 2025

Review Evolution of robotic assisted nephrectomy over time and comparison with laparoscopic assisted nephrectomy: a comprehensive literature review Mriganka Sinha, Mayas Rddah, Karl Spiteri Published: Friday, August 1, 2025

Editorial Chrono-targeting the prostate: a hypothesis on circadian regulation of androgen receptor activity in benign prostatic hyperplasia Ivan Bivolarski Published: Friday, August 22, 2025

Case Report A novel combined laparoscopic and transurethral resection technique for urachal adenocarcinoma: technique description and literature review Ahmed Yousef, Ghazy Kassem, Nasreldin Mohammed Published: Friday, September 5, 2025

Review Surgical approach and atypical recurrence after radical nephrectomy: considerations for cytoreductive nephrectomy in the metastatic setting Rachel C. Bernardo, Michael Wynne, Michelle Wang, Diego Gonzalez, Sam Kwon, Fiona Wardrop, Michael Whalen Published: Monday, September 29, 2025

Commentary Application of the prostate health index in the early diagnosis and treatment of prostate cancer Gerard Hennery Published: Monday, September 29, 2025

Research Article Cigarette exposure and aging pathways: interplay between IGF-1 suppression and TGF-β increase Titiek Hidayati, Akrom Akrom, Suny Sun Published: Sunday, September 28, 2025

Review Epigenetic mechanisms of the influence of aging on the development of breast cancer with the participation of retroelements Rustam Mustafin Published: Friday, August 15, 2025

Research Article Integrative bioinformatics and molecular docking unveil multi-target therapeutic mechanisms of Coptidis Rhizoma (CR) against Lewy body dementia (LBD): an in-silico approach Pranab Dev Sharma, Abdullah Al Noman Published: Friday, June 6, 2025

Review Resilience in the depths: anemones as models for aging and regeneration research Pooja B. Rasal, Gaurav N. Kasar, Durgesh S. Pagar, Aman B. Upaganlawar, Sunil K. Mahajan Published: Friday, July 18, 2025

Review Epigenetic mechanisms of the influence of aging on the development of breast cancer with the participation of retroelements Rustam Mustafin Published: Friday, August 15, 2025

Letter to Editor Sarcopenia and intrinsic capacity in aging: implications for geriatric physiotherapy assessment and care Weslley Barbosa Sales, Melissa Silva Rocha Pereira Published: Friday, August 29, 2025

Research Article Experimental confirmation of osteoarthritis repair in vivo using epigenetic reprogramming with small molecules Javdat Muratkhodjaev, Saodat A. Muratkhodjaeva, Tamara U. Aripova Published: Monday, September 8, 2025

Letter to Editor Expanding the clinical implications of biomarkers and physiological indicators in geriatric institutionalization Jitendra Sinha, Shampa Ghosh, Krishna Singh Published: Thursday, September 11, 2025

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