Denudation type of transurethral resection for bladder tumor | Yang | Clinical Surgery Research Communications

Denudation type of transurethral resection for bladder tumor

Xiao-feng Yang, Xiao-jing Zhang, Hua Yang, Wei Zhang, Dong-wen Wang

Abstract


Objective: To investigate the safety and effectiveness of a denudation type of transurethral resection for bladder tumor (D-TURBT).

Methods: From December, 2000 to December, 2011, a total of 114 patients with nonmuscle invasive bladder cancer (NMIBC) were treated using D-TURBT by the same urologist for 121 person-times. The key steps of D-TURBT included removal of the visible tumors, electrocoagulation of the tumor basement membrane, and loop-electroexcision push-pull denudation of the coagulated tissues to expose the normal submucosa or muscle. The patients were followed up for 4.82±4.1 years postoperatively to observe the efficacy and complications of D-TURBT.

Results: Among the 114 cases, 96 (84.21%) had no recurrence after the first D-TURB, but 18 cases (15.79%) relapsed. Those 18 patients underwent a second D-TURB; 13 (72.2%) had no further relapse, but 5 cases had a second relapse. Those 5 patients underwent a third D-TURB; 2 of those cases had no further recurrence, but the other 3 had a third recurrence. Of those 3, 2 had distant metastasis, and 1 refused further treatment. During the follow-up, no patient experienced bladder perforation or was converted to open surgery. Only 2 (1.75%) of the 114 cases showed worsened clinical staging, while 111 cases were tumor-free, for an overall response rate of 97.37% (111/114).

Conclusion: D-TURBT is an improved surgical approach. It removes NMIBC more effectively than conventional TURBT, while avoiding residual tumor and reducing the relapse rate. D-TURBT is an effective, safe, simple, and easy approach for treating NMIBC.



Subscribe to receive issue release notifications
and newsletters from journals