Posted On 2023-05-23

Guest Editor: Prof. Dr. Alexander Panossian

Phytomed AB, Vaxtorp, Sweden.



Dear Colleagues,

Recent progress in Phytotherapy research is currently associated with the rapid development of network pharmacology and systems biology concepts, which provide the tools both for the understanding of molecular mechanisms and modes of action of plant extracts used in traditional medicinal systems and purified active constituents and for the discoveries of new effective and safe therapeutic agents.

Many components of the neuroendocrine-immune system mediate the effects of various herbal preparations used for preventing and treatment of aging-induced diseases and disorders, such as neurodegenerative diseases (Alzheimer's disease, etc.), atherosclerosis - thrombosis, infarction, stroke, cardiovascular disease and hypertension,  cancer, degenerative joint disease (osteoarthritis), type 2 diabetes, obesity,  muscle degeneration (sarcopenia), visual loss because of clouding of the lens  (cataracts), low grade chronic systemic inflammation (inflammaging), cell degeneration, cellular senescence, etc. 

However, rational and evidence-based use of selected herbal preparations is required for the effective and safe treatment of various aging-related diseases.

This Special Issue is aimed to highlight recent achievements, findings, and observations in phytotherapy of aging-related disorders, based on network pharmacology and systems biology approach.

We encourage authors to submit the results of clinical and preclinical in vivo and in vitro studies of herbal preparations and purified compounds.

Dr. Alexander Panossian
Guest Editor


Completion Date

February 28, 2023



· Systems biology

· Network pharmacology

· Phytotherapy

· Aging disorders

· Cellular senescence

· Inflammaging

· Medicinal plants



Thomas Efferth, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
Hongxun Tao, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China.
Tatjana Kundakovi?,Univ Belgrade, Dept Pharmacognosy, Fac Pharm, Vojode Stepe 450, Belgrade 11221, Serbia.
Luiz Claudio Di Stasi, Univ Estadual Paulista UNESP, Lab Phytomed Pharmacol & Biotechnol PhytoPharmaTe, Dept Pharmacol, Inst Biosci, BR-18618000 Botucatu, SP, Brazil.
Siyaram Pandey, Univ Windsor, Dept Chem & Biochem, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada.
Ivana Beatrice Monica da Cruz, Post-Graduate Program in Gerontology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.
Tzu-Shing Deng, Department of Agronomy, National Chung Hsing University, Taichung 402, Taiwan.
Raquel Abalo, Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
Shyam Sunder Chatterjee, Stettiner Straße 1, D-76138 Karlsruhe, Germany.

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